Sample Size and Power Calculations using the APPLE and SEPPLE
Methods
Zhenzhen Xu <Zhenzhen.Xu@fda.hhs.gov> , Boguang Zhen<Boguang.Zhen@fda.hhs.gov>, Yongsoek Park <yongpark@pitt.edu> and Bin Zhu <bin.zhu@nih.gov>
Provides sample size and power calculations when the treatment time-lag effect is present and the lag duration is homogeneous across the individual subject. The methods used are described in Xu, Z., Zhen, B., Park, Y., & Zhu, B. (2017) <doi:10.1002/sim.7157>.

person("Antonio", "Rodriguez", email = "tonirodriguezcontesti@gmail.com", role = c("aut", "cre"))
Measure of agreement Delta was originally by Martín & Femia (2004) <DOI:10.1348/000711004849268>.
Since then has been considered as agreement measure for different
fields, since their behavior is usually better than the usual Kappa index
by Cohen (1960) <DOI:10.1177/001316446002000104>. The main issue with Delta
is that can not be computed by hand contrary to Kappa.

c(person("Antonio", "Rodriguez", email = "tonirodriguezcontesti@gmail.com", role = c("aut", "cre")),
person("Pedro", "Femia", email = "pfemia@ugr.es", role = c("aut", "cph")),
person("Antonio", "Martín", email = "amartina@ugr.es", role = c("aut", "cph")))
Antonio Rodriguez [aut, cre],
Pedro Femia [aut, cph],
Antonio Martín [aut, cph]

Measure of agreement delta was originally by Martín & Femia (2004) <DOI:10.1348/000711004849268>.
Since then has been considered as agreement measure for different
fields, since their behavior is usually better than the usual kappa index
by Cohen (1960) <DOI:10.1177/001316446002000104>. The main issue with delta
is that can not be computed by hand contrary to kappa. The current algorithm
is based on the Version 5 of the delta windows program that can be found on
<https://www.ugr.es/~bioest/software/delta/cmd.php?seccion=downloads>.

c(person("Antonio", "Rodriguez", email = "tonirodriguezcontesti@gmail.com", role = c("aut", "cre")),
person("Pedro", "Femia", email = "pfemia@ugr.es", role = c("cph", "ctb")),
person("Antonio", "Martin", email = "amartina@ugr.es", role = c("cph", "ctb")))
Antonio Rodriguez [aut, cre],
Pedro Femia [cph, ctb],
Antonio Martin [cph, ctb]