Purpose of this package is it to plan, monitor and evaluate
oncological phase II studies. In general this kind of studies are single-arm
trials with planned interim analysis and binary endpoint. To meet the resulting
requirements, the package provides functions to calculate and evaluate 'Simon's
two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with
this package a good starting point is to take a closer look at the functions
getSolutions() and getSolutionsSub1().The web-based tool (https://imbi.shinyapps.io/phaseII-app/)
extends the functionality of our R package by means of a proper dealing with over- and underrunning.
The R function binom.test of the 'stats' R package and the package 'binom' might be
helpful to assess the performance of the corresponding one-stage design as a reference.

Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate "Simon's two-stage designs" and so called "subset designs". If you are unfamiliar with this package a good starting point is to take a closer look at the functions "getSolutions" and "getSolutionsSub1".

Planning, Conducting, and Analysing Single-Arm Phase II Studies
Purpose of this package is it to plan, monitor and evaluate
oncological phase II studies. In general this kind of studies are single-arm
trials with planned interim analysis and binary endpoint. To meet the resulting
requirements, the package provides functions to calculate and evaluate 'Simon's
two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with
this package a good starting point is to take a closer look at the functions
getSolutions() and getSolutionsSub1().The web-based tool (<https://imbi.shinyapps.io/phaseII-app/>)
extends the functionality of our R package by means of a proper dealing with over- and underrunning.
The R function binom.test of the 'stats' R package and the package 'binom' might be
helpful to assess the performance of the corresponding one-stage design as a reference.