numDeriv, Rsolnp, quadprog, parallel, multcomp

Planning and Analyzing Dose Finding Experiments

c(
person("Bjoern", "Bornkamp", email = "bbnkmp@gmail.com", comment = c(ORCID = "0000-0002-6294-8185"), role = c("aut", "cre")),
person("Jose", "Pinheiro", role = "ctb"),
person("Frank", "Bretz", role = "ctb"))
The DoseFinding package provides functions for the design and analysis
of dose-finding experiments (with focus on pharmaceutical Phase
II clinical trials). It provides functions for: multiple contrast
tests, fitting non-linear dose-response models (using Bayesian and
non-Bayesian estimation), calculating optimal designs and an
implementation of the MCPMod methodology (Pinheiro et al. (2014)
<doi:10.1002/sim.6052>).
Bjoern Bornkamp [aut, cre] (<https://orcid.org/0000-0002-6294-8185>),
Jose Pinheiro [ctb],
Frank Bretz [ctb]

c(
person("Bjoern", "Bornkamp", email = "bbnkmp@mail.de", comment = c(ORCID = "0000-0002-6294-8185"), role = c("aut", "cre")),
person("Jose", "Pinheiro", role = "aut"),
person("Frank", "Bretz", role = "aut"),
person("Ludger", "Sandig", role = "aut"))
numDeriv, Rsolnp, quadprog, parallel, multcomp, ggplot2,
knitr, rmarkdown, MASS, testthat
Bjoern Bornkamp [aut, cre] (<https://orcid.org/0000-0002-6294-8185>),
Jose Pinheiro [aut],
Frank Bretz [aut],
Ludger Sandig [aut]

Test against parametric regression function
Performs hypothesis tests concerning a regression function in a least-squares model, where the null is a parametric function, and the alternative is the union of large-dimensional convex polyhedral cones.
graphics, grDevices, stats, utils, coneproj, Matrix, MASS

Test Against Parametric Regression Function
Performs hypothesis tests concerning a regression function in a least-squares model, where the null is a parametric function, and the alternative is the union of large-dimensional convex polyhedral cones. See Bodhisattva Sen and Mary C Meyer (2016) <doi:10.1111/rssb.12178> for more details.
graphics, grDevices, stats, utils, coneproj (>= 1.12), Matrix,
MASS