Miscellaneous useful or interesting functions.

This package estimates gaussian cluster weighted linear
regressions by EM algorithm.

This package estimates gaussian cluster weighted linear regressions by EM algorithm.

Cauchy Weighted Joint Test for Pharmacogenetics Analysis
c(
person(given="Hong", family="Zhang",
email="hzhang@wpi.edu", role = c("aut", "cre"),
comment=c(ORCID = "0000-0002-8869-8671"))
)
A flexible and robust joint test of the single nucleotide polymorphism (SNP) main effect and genotype-by-treatment interaction effect for continuous and binary endpoints. Two analytic procedures, Cauchy weighted joint test (CWOT) and adaptively weighted joint test (AWOT), are proposed to accurately calculate the joint test p-value. The proposed methods are evaluated through extensive simulations under various scenarios. The results show that the proposed AWOT and CWOT control type I error well and outperform existing methods in detecting the most interesting signal patterns in pharmacogenetics (PGx) association studies. For reference, see Hong Zhang, Devan Mehrotra and Judong Shen (2022) <doi:10.13140/RG.2.2.28323.53280>.

c(
person("C. B.", "Barber", role="cph", comment="author of the Qhull library"),
person("The Geometry Center", role="cph"),
person("Stéphane", "Laurent", role=c("cph","aut","cre"), email="laurent_step@yahoo.fr"))
Computes the convex hull in arbitrary dimension, based on the Qhull library (<http://www.qhull.org>). The package provides a complete description of the convex hull: edges, ridges, facets, adjacencies. Triangulation is optional.
C. B. Barber [cph] (author of the Qhull library),
The Geometry Center [cph],
Stéphane Laurent [cph, aut, cre]

c(
person("C. B.", "Barber", role="cph", comment="author of the Qhull library"),
person("The Geometry Center", role="cph"),
person("Stéphane", "Laurent", role=c("cph","aut","cre"), email="laurent_step@outlook.fr"))

c(
person("C. B.", "Barber", role = "cph",
comment = "author of the Qhull library"),
person("The Geometry Center", role = "cph"),
person("Stéphane", "Laurent", , "laurent_step@outlook.fr", role = c("cph", "aut", "cre"))
)
Computes the convex hull in arbitrary dimension, based on the
Qhull library (<http://www.qhull.org>). The package provides a
complete description of the convex hull: edges, ridges, facets,
adjacencies. Triangulation is optional.