Tools for Normalizing and Comparing ChIP-seq Samples
person("Shiqi", "Tu", email = "tushiqi@picb.ac.cn",
role = c("aut", "cre"),
comment = c(ORCID = "0000-0003-3534-5714"))
Chromatin immunoprecipitation followed by high-throughput
sequencing (ChIP-seq) is the premier technology for profiling genome-wide
localization of chromatin-binding proteins, including transcription
factors and histones with various modifications.
This package provides a robust method for normalizing ChIP-seq
signals across individual samples or groups of samples. It also designs
a self-contained system of statistical models for calling differential
ChIP-seq signals between two or more biological conditions as well as
for calling hypervariable ChIP-seq signals across samples. Refer to
Tu et al. (2021) <doi:10.1101/gr.262675.120> and
Chen et al. (2021) <doi:10.1101/2021.07.27.453915>
for associated statistical details.
stats, graphics, methods, locfit (>= 1.5.9), scales (>=
0.3.0), statmod (>= 1.4.34)
gplots (>= 3.0.1), DescTools (>= 0.99.24), knitr, rmarkdown

Chromatin immunoprecipitation followed by high-throughput
sequencing (ChIP-seq) is the premier technology for profiling genome-wide
localization of chromatin-binding proteins, including transcription
factors and histones with various modifications.
This package provides a robust method for normalizing ChIP-seq
signals across individual samples or groups of samples. It also designs
a self-contained system of statistical models for calling differential
ChIP-seq signals between two or more biological conditions as well as
for calling hypervariable ChIP-seq signals across samples. Refer to
Tu et al. (2021) <doi:10.1101/gr.262675.120> and
Chen et al. (2022) <doi:10.1186/s13059-022-02627-9>
for associated statistical details.

Andrew O. Finley <afinley@stat.umn.edu>, Sudipto Banerjee <sudiptob@biostat.umn.edu>
Scattered data interpolation with Multilevel B-Splines

Andrew O. Finley <finleya@msu.edu>, Sudipto Banerjee <sudiptob@biostat.umn.edu>

Andrew O. Finley <finleya@msu.edu>, Sudipto Banerjee
<sudiptob@biostat.umn.edu>