Inference and Prediction of Generic Physiologically-Based
Kinetic Models
c(
person("Virgile", "Baudrot", role = c("aut","cre"), email = "virgile.baudrot@qonfluens.com"),
person("Sandrine", "Charles", role = "aut"),
person("Christelle", "Lopes", role = "aut"),
person("Ophélia", "Gestin", role = "ctb"),
person("Dominique", "Lamonica", role = "ctb"),
person("Aurélie", "Siberchicot", role = "ctb")
)
Fit and simulate any kind of
physiologically-based kinetic ('PBK') models whatever the number of compartments.
Moreover, it allows to account for any link between pairs of compartments, as
well as any link of each of the compartments with the external medium. Such
generic PBK models have today applications in pharmacology (PBPK models) to
describe drug effects, in toxicology and ecotoxicology (PBTK models) to describe
chemical substance effects. In case of exposure to a parent compound (drug or
chemical) the 'rPBK' package allows to consider metabolites, whatever their number
and their phase (I, II, ...). Last but not least, package 'rPBK' can also be used for
dynamic flux balance analysis (dFBA) to deal with metabolic networks. See also
Charles et al. (2022) <doi:10.1101/2022.04.29.490045>.
Virgile Baudrot [aut, cre],
Sandrine Charles [aut],
Christelle Lopes [aut],
Ophélia Gestin [ctb],
Dominique Lamonica [ctb],
Aurélie Siberchicot [ctb]

Packed bar charts are a variation of treemaps for visualizing skewed data.  The concept was introduced by Xan Gregg at 'JMP'.

Download and Merge Single-Cell RNA-Seq Data from the PanglaoDB
Database
c(person("Daniel","Osorio", email = "daniecos@uio.no", role = c("aut","cre"), comment = c(ORCID = "0000-0003-4424-8422")),
person("Marieke","Kuijjer", role = c("aut"), comment = c(ORCID = "0000-0001-6280-3130")),
person("James J.","Cai", role = c("aut"), comment = c(ORCID = "0000-0002-8081-6725")))
Download and merge labeled single-cell RNA-seq data from the PanglaoDB <https://panglaodb.se/> into a Seurat object.
methods, XML, xml2, Seurat, pbapply, Matrix