The TEQR package contains software to calculate the operating characteristics for the TEQR and the ACT designs.The TEQR (toxicity equivalence range) design is a toxicity based cumulative cohort design with added safety rules. The ACT (Activity constrained for toxicity) design  is also a cumulative cohort design with additional safety rules. The unique feature of this design is that dose is escalated based on lack of activity rather than on lack of toxicity and is de-escalated only if an unacceptable level of toxicity is experienced.

Test for A+B Traditional Escalation Rule
This package is for the comparison of various types of A+B
escalation rules for dose finding trials.

Fast simulation of reconstructed phylogenetic trees under
time-dependent birth-death processes
TESS is a package for simulation of reconstructed
phylogenetic trees under global, time-dependent birth-death
processes. Speciation and extinction rates can be any function
of time and mass-extinction events at specific times can be
provided. Trees can be simulated either conditioned on the
number of species, the time of the process, or both.
Additionally, the likelihood equations are implemented for
convenience and can be used for Maximum Likelihood (ML)
estimation and Bayesian inference.

Diversification Rate Estimation and Fast Simulation of
Reconstructed Phylogenetic Trees under Tree-Wide
Time-Heterogeneous Birth-Death Processes Including
Mass-Extinction Events
Simulation of reconstructed phylogenetic trees under tree-wide time-heterogeneous birth-death processes and estimation of diversification parameters under the same model. Speciation and extinction rates can be any function of time and mass-extinction events at specific times can be provided. Trees can be simulated either conditioned on the number of species, the time of the process, or both. Additionally, the likelihood equations are implemented for convenience and can be used for Maximum Likelihood (ML) estimation and Bayesian inference.

Derek Beaton, Jenny Rieck, Cherise R. Chin Fatt, Herve Abdi
TExPosition is an extension of ExPosition for two table
analyses, specifically, discriminant analyses.