Inference about the standardized mortality ratio when evaluating
the effect of a screening program on survival.
The InferenceSMR package provides functions to make
inference about the standardized mortality ratio (SMR) when
evaluating the effect of a screening program. The package is
based on methods described in Sasieni (2003) and Talbot et al.
(2011).

Estimate and Account for Tumor Purity in Cancer Methylation Data
Analysis
The proportion of cancer cells in solid tumor sample, known as the tumor purity, has adverse impact on a variety of data analyses if not properly accounted for. We develop 'InfiniumPurify', which is a comprehensive R package for estimating and accounting for tumor purity based on DNA methylation Infinium 450k array data. 'InfiniumPurify' provides functionalities for tumor purity estimation. In addition, it can perform differential methylation detection and tumor sample clustering with the consideration of tumor purities.

c(person("Pedro", "Costa Ferreira", email = "pedro.guilherme@fgv.br", role = c("aut", "cre")),
person("Daiane", "Marcolino", email = "daiane.marcolino@fgv.br", role = "aut"),
person("Talitha", "Speranza", email = "talitha.speranza@fgv.br", role = "aut"),
person("Fernando", "Teixeira", email = "fernando.teixeira@fgv.br", role = "aut"))
Provides access to core inflation functions. Four different core inflation
functions are provided. The well known trimmed means, exclusion and double weighing methods,
alongside the new Triple Filter method introduced in Ferreira et al. (2016) <https://goo.gl/UYLhcj>.
Pedro Costa Ferreira [aut, cre],
Daiane Marcolino [aut],
Talitha Speranza [aut],
Fernando Teixeira [aut]

Melt Curve Fitting and Melt Shift Analysis
c(person("Neil", "McCracken", email = "namccrac@iu.edu",role = c("aut")),
person("Aruna", "Wijeratne", role = c("ctb")),
person("Amber", "Mosley", email = "almosley@iu.edu",role = c("cre")))
This program analyzes raw abundance data from a cellular thermal shift experiment and calculates melt temperatures and melt shifts for each protein in the experiment. Reference to software development can be found at <doi:10.1101/2020.10.31.363523>.
readxl, writexl, optimr, data.table, plotrix, tidyr, ggplot2
Neil McCracken [aut],
Aruna Wijeratne [ctb],
Amber Mosley [cre]