Simulations to predict the number of loci expected in RAD and
GBS approaches.
c(person("Olivier", "Lepais", role=c("aut", "cre"), email = "olepais@st-pee.inra.fr"), person("Jason", "Weir", role=c("aut")))
This package provides a number of functions to simulate restriction enzyme digestion, library construction and fragments size selection to predict the number of loci expected from most of the Restriction site Associated DNA (RAD) and Genotyping By Sequencing (GBS) approaches. SimRAD aims is to provide an estimation of the number of loci expected from a particular genome depending on the protocol type and parameters allowing to assess feasibility, multiplexing capacity and the amount of sequencing required.
Olivier Lepais [aut, cre],
Jason Weir [aut]

Simulations to Predict the Number of RAD and GBS Loci
Provides a number of functions to simulate restriction enzyme digestion, library construction and fragments size selection to predict the number of loci expected from most of the Restriction site Associated DNA (RAD) and Genotyping By Sequencing (GBS) approaches. SimRAD estimates the number of loci expected from a particular genome depending on the protocol type and parameters allowing to assess feasibility, multiplexing capacity and the amount of sequencing required.

Simulate Pedigrees Ascertained for a Rare Disease
c(person("Christina", "Nieuwoudt",
role = c("aut", "cre"),
email = "cnieuwou@sfu.ca"),
person("Jinko", "Graham", role = "aut"))
Routines to simulate and manipulate pedigrees ascertained to
contain multiple family members affected by a rare disease.
Christina Nieuwoudt, Samantha J Jones, Angela Brooks-Wilson,
and Jinko Graham (2017) <doi:10.1101/234153>.
Christina Nieuwoudt [aut, cre],
Jinko Graham [aut]

Routines to simulate and manipulate pedigrees ascertained to
contain multiple family members affected by a rare disease.
Christina Nieuwoudt, Samantha J Jones, Angela Brooks-Wilson,
and Jinko Graham (2018) <doi:10.1101/234153>.

Simulate Genetic Sequence Data for Pedigrees
Methods to simulate genetic sequence data for pedigrees, with
functionality to simulate genetic heterogeneity among pedigrees.
Christina Nieuwoudt, Angela Brooks-Wilson,
and Jinko Graham (2019) <doi:10.1101/534552>.
knitr (>= 1.13), rmarkdown (>= 0.9.6), testthat