This package provides the estimation of an index measuring
the clinical utility of DNA testing in the context of
gene-environment interactions on a disease. The corresponding
gene-environment interaction effect on the additive scale can
also be obtained. The estimation is based on case-control or
cohort data. The method was developed by Nguyen et al. 2013.

General Utility Functions for Analysis of Clinical Data
c(
person(given = "Laure", family = "Cougnaud", role = "aut",
email = "laure.cougnaud@openanalytics.eu"),
person(given = "Michela", family = "Pasetto", role = c("aut", "cre"),
email = "michela.pasetto@openanalytics.eu")
)
Utility functions to facilitate the import,
the reporting and analysis of clinical data.
Example datasets in 'SDTM' and 'ADaM' format, containing a subset of patients/domains
from the 'CDISC Pilot 01 study' are also available as R datasets to demonstrate
the package functionalities.
crosstalk, data.table, DT, haven, htmlwidgets, knitr, plyr,
tools, utils, viridisLite
dplyr, ggplot2, plotly, htmltools, jsonlite, pander,
rmarkdown, testthat, xml2, flextable
Laure Cougnaud [aut],
Michela Pasetto [aut, cre]

c(
person(given = "Laure", family = "Cougnaud", role = "aut",
email = "laure.cougnaud@openanalytics.eu"),
person(given = "Michela", family = "Pasetto", role = c("aut", "cre"),
email = "michela.pasetto@openanalytics.eu"),
person(given = "Open Analytics", role = "cph")
)
dplyr, tibble, ggplot2, plotly, htmltools, pander, rmarkdown,
testthat, flextable
pandoc (for inclusion of list of interactive
plots/objects with knitr)
Laure Cougnaud [aut],
Michela Pasetto [aut, cre],
Open Analytics [cph]

c(
person(given = "Laure", family = "Cougnaud", role = c("aut", "cre"),
email = "laure.cougnaud@openanalytics.eu"),
person(given = "Michela", family = "Pasetto", role = "aut",
email = "michela.pasetto@openanalytics.eu"),
person(given = "Open Analytics", role = "cph")
)
Laure Cougnaud [aut, cre],
Michela Pasetto [aut],
Open Analytics [cph]

c(
person(given = "Laure", family = "Cougnaud", role = c("aut", "cre"),
email = "laure.cougnaud@openanalytics.eu"),
person(given = "Michela", family = "Pasetto", role = "aut",
email = "michela.pasetto@openanalytics.eu"),
person(given = "Arne", family = "De Roeck",
role = "rev", comment = "tests"),
person(given = "Open Analytics", role = "cph")
)
tibble, ggplot2, plotly, htmltools, pander, rmarkdown,
testthat, flextable
Laure Cougnaud [aut, cre],
Michela Pasetto [aut],
Arne De Roeck [rev] (tests),
Open Analytics [cph]