Normalised Prediction Distribution Errors for Nonlinear
Mixed-Effect Models
c(person(given = "Emmanuelle",
family = "Comets",
role = c("aut", "cre"),
email = "emmanuelle.comets@inserm.fr",
comment = c(ORCID = "0000-0002-9150-9886")),
person(given = "Karl",
family = "Brendel",
role = "ctb"),
person(given = "Thi Huyen Tram",
family = "Nguyen",
role = "ctb"),
person(given = "Romain",
family = "Leroux",
role = "ctb"),
person(given = "France",
family = "Mentre",
role = "ctb"))
Provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics. Documentation about 'npde' is provided by a comprehensive user guide on the github repository (<https://github.com/ecomets/npde30/blob/main/userguide_npde_3.0.pdf>), and references concerning the methods include the papers by Brendel et al. (2006, <doi:10.1007/s11095-006-9067-5>; 2010, <doi:10.1007/s10928-009-9143-7>), Comets et al. (2008, <doi:10.1016/j.cmpb.2007.12.002> ; 2010, <http://journal-sfds.fr/article/view/45>), and Nguyen et al. (2012, <doi:10.1007/s10928-012-9264-2>). See 'citation("npde")' for details.
methods, scales, mclust, testthat, rlang
'NpdeSimData.R' 'NpdeData.R' 'aaa_generics.R'
'NpdeData-methods.R' 'NpdeRes.R' 'NpdeRes-methods.R'
'NpdeObject.R' 'NpdeObject-methods.R' 'compute_distribution.R'
'compute_npde.R' 'compute_pd.R' 'compute_ploq.R' 'mainNpde.R'
'npde.R' 'npdeControl.R' 'plotNpde-auxDistPlot.R'
'plotNpde-auxScatter.R' 'plotNpde-auxScatterPlot.R'
'plotNpde-binningPI.R' 'plotNpde-covplot.R'
'plotNpde-distributionPlot.R' 'plotNpde-methods.R'
'plotNpde-plotFunctions.R' 'plotNpde-scatterplot.R'
Emmanuelle Comets [aut, cre] (<https://orcid.org/0000-0002-9150-9886>),
Karl Brendel [ctb],
Thi Huyen Tram Nguyen [ctb],
Romain Leroux [ctb],
France Mentre [ctb]

c(person(given = "Emmanuelle",
family = "Comets",
role = c("aut", "cre"),
email = "emmanuelle.comets@inserm.fr",
comment = c(ORCID = "0000-0002-9150-9886")),
person(given = "Karl",
family = "Brendel",
role = "ctb"),
person(given = "Thi Huyen Tram",
family = "Nguyen",
role = "ctb"),
person(given="Marc",
family="Cerou",
role = "ctb"),
person(given = "Romain",
family = "Leroux",
role = "ctb"),
person(given = "France",
family = "Mentre",
role = "ctb"))
Provides routines to compute normalised prediction distribution errors, a metric designed to evaluate non-linear mixed effect models such as those used in pharmacokinetics and pharmacodynamics.
methods, scales, ggplot2, mclust, grid, gridExtra, testthat,
rlang
Emmanuelle Comets [aut, cre] (<https://orcid.org/0000-0002-9150-9886>),
Karl Brendel [ctb],
Thi Huyen Tram Nguyen [ctb],
Marc Cerou [ctb],
Romain Leroux [ctb],
France Mentre [ctb]