The package can prioritize candidate disease metabolites based
on global functional relationships between metabolites in the
context of metabolic pathways
The package can prioritize the candidate disease metabolites based on the assumption
that functionally related metabolites tend to associate with the same or similar
diseases in the context of metabolic pathway. The PROFANCY package (1) prioritizes the
disease metabolites from global functional similarity and local modularity of the
metabolic network; (2) allows users to select default metabolites or input their
interested metabolites as seed nodes or candidate nodes (3) can prioritize the candidate
metabolites in KEGG or EHMN metabolic network.

Generic Coordinate System Transformations Using 'PROJ'
c(person(given = "Michael D.",
family = "Sumner",
role = c("aut", "cre"),
email = "mdsumner@gmail.com",
comment = c(ORCID = "0000-0002-2471-7511")),
person("Jeroen", "Ooms", role = c("ctb"),
comment = "provided PROJ library support on Windows, and assistance with Windows configuration"),
person("Simon", "Urbanek", role = c("cph", "ctb"),
comment = "wrote original code versions for PROJ version 6"))
A wrapper around the generic coordinate transformation software 'PROJ'
that transforms geospatial coordinates from one coordinate reference system ('CRS') to another. This
includes cartographic projections as well as geodetic transformations. Version 6.0.0 or
higher is required. The intention is for this package to be used by user-packages such
as 'reproj', and that the older 'PROJ.4' and version 5 pathways be provided by the
legacy package. The 'PROJ' library is available from <https://proj.org/>.
testthat (>= 2.1.0), covr, spelling, knitr, rmarkdown
Michael D. Sumner [aut, cre] (<https://orcid.org/0000-0002-2471-7511>),
Jeroen Ooms [ctb] (provided PROJ library support on Windows, and
assistance with Windows configuration),
Simon Urbanek [cph, ctb] (wrote original code versions for PROJ version
6)

A wrapper around the generic coordinate transformation software 'PROJ'
that transforms geospatial coordinates from one coordinate reference system ('CRS')
to another. This includes cartographic projections as well as geodetic transformations.
Version 6.0.0 or higher is required, earlier versions if available are not used
leaving this package harmlessly non-functional. The intention is for this package
to be used by user-packages such as 'reproj', and that the older 'PROJ.4' and version 5
pathways be provided by the 'proj4' package. Separating this disruptive version
change (from 4.0 and 5.0, to 6.0 and above) allows the use of existing and
stable code in 'proj4' alongside the new idioms and requirements of modern 'PROJ'
using this package. The 'PROJ' library is available from <https://proj.org/>.
proj (>= 6.0.0 required for full operation, package
will install and pass check with lower versions or even if no
PROJ available)