dplyr (>= 0.5.0), digest, nlme, parallel, purrr, rlang, stats,
tidyr, tibble, utils

Pharmacokinetic and Pharmacodynamic Data Management Functions
c(
person("Devin", "Pastoor",
email = "devin.pastoor@gmail.com", role = c("aut", "cre")))
A toolbox for data management common to
pharmacokinetic and pharmacokinetic modeling and simulation, such as resampling,
area-under-the-curve calculation, data chunking, custom csv output,
and project scaffolding.
dplyr (>= 0.5.0), data.table, ggplot2, lazyeval, magrittr,
parallel, purrr, Rcpp (>= 0.12.10), readr (>= 1.0.0), rlang,
stringr, tibble

A toolbox for data management common to pharmacokinetic and
pharmacokinetic modeling and simulation, such as resampling,
area-under-the-curve calculation, data chunking, custom csv
output, and project scaffolding.

Anne Dubois, Julie Bertand, France Mentre and Douglas Bates
Provides functions to evaluate common
pharmacokinetic/pharmacodynamic models and their gradients.

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations
c(
person("Ron", "Keizer", email = "ron@insight-rx.com", role = c("aut", "cre")),
person("Jasmine", "Hughes", email = "jasmine@insight-rx.com", role = "aut"),
person("Dominic", "Tong", email = "dominic@insight-rx.com", role = "aut"),
person("Kara", "Woo", email = "kara@insight-rx.com", role = c("aut")),
person("InsightRX", role = c("cph", "fnd")))
Rcpp (>= 0.12.9), BH, data.table, stringr, MASS, randtoolbox,
jsonlite, stats, parallel, magrittr
Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).
Ron Keizer [aut, cre],
Jasmine Hughes [aut],
Dominic Tong [aut],
Kara Woo [aut],
InsightRX [cph, fnd]

The Parameter Converter of the Pharmacokinetic Models
Pharmacokinetics is the study of drug absorption, distribution,
metabolism, and excretion. The pharmacokinetics model explains that how the
drug concentration change as the drug moves through the different compartments
of the body. For pharmacokinetic modeling and analysis, it is essential
to understand the basic pharmacokinetic parameters. All parameters are
considered, but only some of parameters are used in the model. Therefore,
we need to convert the estimated parameters to the other parameters after
fitting the specific pharmacokinetic model. This package is developed to help
this converting work. For more detailed explanation of pharmacokinetic
parameters, see "Gabrielsson and Weiner" (2007), "ISBN-10: 9197651001";
"Benet and Zia-Amirhosseini" (1995) <DOI: 10.1177/019262339502300203>;
"Mould and Upton" (2012) <doi:10.1038/psp.2012.4>;
"Mould and Upton" (2013) <doi:10.1038/psp.2013.14>.