William Shannon, Tao Li, Hong Xian, Jia Wang, Elena Deych, Carlos Gonzalez
Functional linear modeling and analysis for actigraphy data.

A Toolbox for Parsing Scored Actigraphy Data
c(person("Edgar", "Santos-Fernandez", , "edgar.santosfdez@gmail.com",
c("aut", "cre")), person("Lora", "Wu", , "L.Wu@massey.ac.nz", c("aut")),
person("Margo", "van den Berg", , "M.J.vandenBerg@massey.ac.nz", c("aut"
)) )
'Actigraphy' is a cost-effective and convenient tool for activity-based monitoring. 'ActisoftR' was designed for parsing 'actigraphy' outputs and to summarise scored data across user-defined intervals. It consists of several functions for importing, generating reports and statistics, and for data visualization.
ggplot2, dplyr, scales, tibble, lubridate, data.table,
magrittr, methods, RColorBrewer, tidyr
DT, Rcpp, rmarkdown, roxygen2, knitr, testthat, readr,
plotly, devtools
Edgar Santos-Fernandez [aut, cre],
Lora Wu [aut],
Margo van den Berg [aut]

c(person("Edgar", "Santos-Fernandez", , "edgar.santosfdez@gmail.com",
c("aut")), person("Lora", "Wu", , "L.Wu@massey.ac.nz", c("aut", "cre")),
person("Margo", "van den Berg", , "M.J.vandenBerg@massey.ac.nz", c("aut"
)) )
Edgar Santos-Fernandez [aut],
Lora Wu [aut, cre],
Margo van den Berg [aut]

A mutation analysis tool that discovers cancer driver genes with frequent mutations in protein signalling sites such as post-translational modifications (phosphorylation, ubiquitination, etc). The Poisson generalised linear regression model identifies genes where cancer mutations in signalling sites are more frequent than expected from the sequence of the entire gene. Integration of mutations with signalling information helps find new driver genes and propose candidate mechanisms to known drivers. Reference: Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers. Juri Reimand and Gary D Bader. Molecular Systems Biology (2013) 9:637 <doi:10.1038/msb.2012.68>.
Finding Cancer Driver Proteins with Enriched Mutations in
Post-Translational Modification Sites
person("Juri", "Reimand", email = "juri.reimand@utoronto.ca", role = c("aut", "cre"))