Common Multiple Testing Procedures and Gatekeeping Procedures
Alex Dmitrienko, Eric Nantz, and Gautier Paux, with
contributions by Thomas Brechenmacher
Implementation of commonly used p-value-based and
parametric multiple testing procedures (computation of adjusted
p-values and simultaneous confidence intervals) and parallel
gatekeeping procedures based on the methodology presented in
the book "Multiple Testing Problems in Pharmaceutical
Statistics" (edited by Alex Dmitrienko, Ajit C. Tamhane and
Frank Bretz) published by Chapman and Hall/CRC Press 2009.

Metabolomic Multivariate and Univariate Analyses
Edoardo Gaude, Dimitrios Spiliotopoulos, Silvia Mari, Andrea
Spitaleri and Michela Ghitti
Preprocessing of metabolomic data (normalization and
scalings); Principal Component Analysis with help tool for
choosing best-separating principal components and automatic
outlier testing; automatic univariate analysis for parametric
and non-parametric data, with report generation (volcano and
box plots); partial least sqaure discriminant analysis
(PLS-DA); orthogonal partial least square discriminant analysis
(OPLS-DA); Statistical Total Correlation Spectroscopy (STOCSY);
Ratio Analysis NMR SpectroscopY (RANSY).

Metabolomic Univariate and Multivariate Analysis
Edoardo Gaude, Francesca Chignola, Dimitrios Spiliotopoulos,
Silvia Mari, Andrea Spitaleri and Michela Ghitti
car, pdist, pls, gplots, mvtnorm, pcaPP, rrcov, robustbase,
gtools, bitops, caTools

car, pdist, pls, gplots, mvtnorm, robustbase, gtools, bitops,
caTools, pcaPP, rrcov

Metabolomics Univariate and Multivariate Analysis
Preprocessing of high-throughput data (normalization and
scalings); Principal Component Analysis with help tool for
choosing best-separating principal components and automatic
testing for outliers; automatic univariate analysis for
parametric and non-parametric data, with generation of specific
reports (volcano and box plots); partial least square
discriminant analysis (PLS-DA); orthogonal partial least square
discriminant analysis (OPLS-DA); Statistical Total Correlation
Spectroscopy (STOCSY); Ratio Analysis Nuclear Magnetic
Resonance (NMR) Spectroscopy (RANSY).