Packaged: 2015-11-26 14:31:38 UTC; wirthsmarius

Package: OneArmPhaseTwoStudy
Type: Package
Title: Planing, Monitoring and Evaluating Oncological Phase 2 Studies
Version: 0.1.6
Date: 2016-05-23
Author: Marius Wirths
Maintainer: Marius Wirths <wirths@imbi.uni-heidelberg.de>
Description: Purpose of this package is it to plan, monitor and evaluate
oncological phase II studies. In general this kind of studies are single-arm
trials with planned interim analysis and binary endpoint. To meet the resulting
requirements, the package provides functions to calculate and evaluate 'Simon's
two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with
this package a good starting point is to take a closer look at the functions
getSolutions() and getSolutionsSub1().The web-based tool (https://imbi.shinyapps.io/phaseII-app/)
extends the functionality of our R package by means of a proper dealing with over- and underrunning.
The R function binom.test of the 'stats' R package and the package 'binom' might be
helpful to assess the performance of the corresponding one-stage design as a reference.
License: GPL (>= 2)
Depends: methods, stats, Rcpp (>= 0.9.11), R (>= 3.1.0)
LinkingTo: Rcpp
RcppModules: simon, sub1
RoxygenNote: 5.0.1
NeedsCompilation: yes
Packaged: 2016-05-23 08:55:32 UTC; wirthsmarius
Repository: CRAN
Date/Publication: 2016-05-23 11:28:04

Description: Purpose of this package is it to plan, monitor and evaluate oncological phase II studies. In general this kind of studies are single-arm trials with planned interim analysis and binary endpoint. To meet the resulting requirements, the package provides functions to calculate and evaluate "Simon's two-stage designs" and so called "subset designs". If you are unfamiliar with this package a good starting point is to take a closer look at the functions "getSolutions" and "getSolutionsSub1".
Packaged: 2014-12-10 09:56:19 UTC; wirthsmarius

Title: Planning, Conducting, and Analysing Single-Arm Phase II Studies
getSolutions() and getSolutionsSub1().The web-based tool (<https://imbi.shinyapps.io/phaseII-app/>)