Author: Alexander Jueterbock, Philipp Kraemer, Gabriele Gerlach and Jana Deppermann
(Nei, 1973) and the differentiation index D (Jost, 2008) pairwise
between or averaged over several populations.  P-values, stating the
significance of differentiation, and 95 percent confidence intervals
can be estimated using bootstrap resamplings. In the case that more
than two populations are compared pairwise, the p-values are
adjusted by bonferroni correction and in several other ways due to
the multiple comparison from one data set.

Package: DEMEtics
Type: Package
Title: Calculation of Gst and D values characterizing the genetic
differentiation between populations.
Version: 0.8.0
Date: 2010-02-11
Author: Alexander Jueterbock, Philipp Kraemer, Gabriele Gerlach and
Jana Deppermann
Maintainer: Alexander Jueterbock, <Alexander-Jueterbock@web.de>
Depends: R (>= 2.8.0)
Description: Out of a table comprising allelic data of at least one
locus for several individuals and from at least two
populations, measurements of genetic differentiation (i.e. D,
Dest, Dest.Chao, Gst and Gst.est (Jost, 2008)) can be
calculated. P-values and 95% confidence intervals are
calculated according to Manly (1997) using a bootstrap method.
Thereby, for each locus, alleles are reallocated over
populations if they are all in Hardy Weinberg Equilibrium
(HWE). If not, the genotypes are reallocated, since alleles can
not be assumed to be inherited independently from each other
(Goudet, 1996). The p-values state how much the empirical found
allocation of alleles over populations differs from an
allocation that could arise by chance alone. In the case that
more than two populations are compared pairwise, the p-values
are adjusted besides using bonferroni correction in several
other ways due to the multiple comparison from one data set.
License: GPL (>= 2)
Literature: Goudet, J., M. Raymond, et al. (1996). Testing
differentiation in diploid populations. Genetics 144(4):
1933-1940. Jost, L. (2008). Gst and its relatives do not
measure differentiation. Molecular Ecology 17(18): 4015-4026.
Manly, B. F. J. Randomization, bootstrap and Monte Carlo
methods in biology. Chapman & Hall, 1997. Nei M., Chesser R.
Estimation of fixation indices and gene diversities. Annals of
Human Genetics, 1983, 47, 253-259. Wright, S. P. Adjusted
P-Values for simultaneous inference. Biometrics, 1992, 48,
1005-1013.
LazyLoad: yes
Packaged: Thu Feb 11 12:56:05 2010; alexj
Repository: CRAN
Date/Publication: 2010-02-11 12:18:50