Package: NNTbiomarker
Type: Package
Title: Calculate Design Parameters for Biomarker Validation Studies
Version: 0.29.11
Date: 2015-08-20
Author: Roger Day
Maintainer: Roger Day <day01@pitt.edu>
Description: Helps a clinical trial team  discuss
the clinical goals  of a well-defined biomarker with a diagnostic,
staging, prognostic, or predictive purpose.  From this discussion will
come a statistical plan for a (non-randomized) validation trial.
Both prospective and retrospective trials are supported. In a specific
focused discussion, investigators should determine the range of
"discomfort" for the NNT, number needed to treat.  The meaning of
the discomfort range, [NNTlower, NNTupper], is that within this range
most physicians would feel discomfort either in treating or withholding
treatment. A pair of NNT values bracketing that range, NNTpos and NNTneg,
become the targets of the study's design.  If the trial can demonstrate
that a positive biomarker test yields an NNT less than NNTlower,
and that a negative biomarker test yields an NNT less than NNTlower,
then the biomarker may be useful for patients. A highlight of the package
is visualization of a "contra-Bayes" theorem, which produces criteria for
retrospective case-controls studies.
License: GPL-3
Imports: shiny, xtable, stringr, magrittr, mvbutils
Collate: aaa.R ifVerboseCat.R sesp-pv-NNT.R achievable.se.sp.R
binom.confint.R NNTintervals.R run.R ROCplots.R argmin.R zzz.R
Suggests: testthat (>= 0.8.1), knitr (>= 1.6), rmarkdown, ggplot2, plyr
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2015-08-20 20:36:16 UTC; Roger
Repository: CRAN
Date/Publication: 2015-08-21 07:38:39

Title: Datasets and Functions to Benchmark Neural Network Packages
Description: Datasets and functions to benchmark (convergence, speed, ease of use) R packages dedicated to regression with neural networks (no classification in this version). The templates for the tested packages are available in the format of R, R Markdown and HTML files at <https://github.com/pkR-pkR/NNbenchmarkTemplates> and <https://akshajverma.com/NNbenchmarkWeb/index.html>.
Author: Patrice Kiener [aut, cre] (<https://orcid.org/0000-0002-0505-9920>),
person("Patrice", "Kiener", role = c("aut", "cre"), email = "rpackages@inmodelia.com", comment = c(ORCID = "0000-0002-0505-9920")),
person("Christophe", "Dutang", role = "aut", email = "christophe.dutang@ensimag.fr", comment = c(ORCID = "0000-0001-6732-1501")),
person("Salsabila", "Mahdi", role = "aut", email = "bila.mahdi@mhs.unsyiah.ac.id"),
person("Akshaj", "Verma", role = "aut", email = "akshajverma7@gmail.com"),
person("Yifu", "Yan", role = "ctb", email = "yanyifu94@hotmail.com")