Depends: R (>= 1.8.0), mice, Rsolnp, nnet

Description: Contains tools for exploring Hardy-Weinberg equilibrium (Hardy, 1908;  Weinberg, 1908) for bi and multi-allelic genetic marker data. All classical tests (chi-square, exact, likelihood-ratio and permutation tests) with bi-allelic variants are included in the package, as well as functions for power computation and for the simulation of marker data under equilibrium and disequilibrium. Routines for dealing with markers on the X-chromosome are included (Graffelman & Weir, 2016) <doi:10.1038/hdy.2016.20>, including Bayesian procedures. Some exact and permutation procedures also work with multi-allelic variants. Special test procedures that jointly address Hardy-Weinberg equilibrium and equality of allele frequencies in both sexes are supplied, for the bi and multi-allelic case. Functions for testing equilibrium in the presence of missing data by using multiple imputation are also provided. Implements several graphics for exploring the equilibrium status of a large set of bi-allelic markers: ternary plots with acceptance regions, log-ratio plots and Q-Q plots. The functionality of the package is explained in detail in a related JSS paper <doi:10.18637/jss.v064.i03>.

Title: Harmonic Regression to One or more Time Series
Maintainer: Paal O. Westermark <pal-olof.westermark@charite.de>
Description: Fits the first harmonics in a Fourier expansion to one or more time series. Trend elimination can be performed.  Computed values include estimates of amplitudes and phases, as well as confidence intervals and p-values for the null hypothesis of Gaussian noise.

Description: Aimed at applying the Harvest classification tree algorithm, which is a modified algorithm of classic classification tree. It was firstly used in drug discovery field, but it also performs well in other kind of data, especially when active region is unrelated.To learn more about the harvest classification algorithm, you can go to http://www.stat.ubc.ca/Research/TechReports/techreports/220.pdf for more information.