Imports: methods, graphics, grDevices, stats, utils

Title: Concentration-Response Data Analysis using Curvep
Authors@R: c(person("Jui-Hua", "Hsieh", email = "juihua.hsieh@gmail.com", role = c("aut", "cre")), person("Alexander", "Sedykh", email = "sunirks@gmail.com", role = c("aut")))
Description: Provide an R interface for processing concentration-response datasets using Curvep, a response noise filtering algorithm. The algorithm was described in the publications (Sedykh A et al. (2011) <doi:10.1289/ehp.1002476> and Sedykh A (2016) <doi:10.1007/978-1-4939-6346-1_14>). Other parametric fitting approaches (e.g., Hill equation) are also adopted for ease of comparison. Also, methods for calculating the confidence interval around the activity metrics are also provided. The methods are based on the bootstrap approach to simulate the datasets (Hsieh J-H et al. <doi:10.1093/toxsci/kfy258>). The simulated datasets can be used to derive the baseline noise threshold in an assay endpoint. This threshold is critical in the toxicological studies to derive the point-of-departure (POD).
Imports: dplyr (>= 0.7), tibble, magrittr, tidyselect, boot, tidyr,
purrr, rlang, stringr, ggplot2, Rdpack, methods
Suggests: testthat, knitr, rmarkdown, tcpl

person("Andrew", "Redd", , "andrew.redd@hsc.utah.edu", c("aut", "cre")),
person("R Documentation Task Force", role=c("aut")
, comment = c(url = "https://rdoctaskforce.github.io/")
Description: Creation and manipulation of R documentation (Rd) as
R objects.  Also contains functions for checking consistency
of Rd and S4 generics and methods for converting
Imports: assertthat, methods, pkgcond, postlogic, purrr, rlang, tools,
Suggests: covr, htmltools, rmarkdown (>= 1.8), stringi, testthat
R Documentation Task Force [aut] (https://rdoctaskforce.github.io/)

person("Andrew", "Redd", role = c("aut", "cre")
person("R Documentation Task Force", role=c("ctb")
, comment = c(url = "https://www.r-consortium.org")
Imports: assertthat, methods, pkgcond, postlogic, purrr, rlang,
Suggests: covr, htmltools, rmarkdown (>= 1.8), stringi
Author: Andrew Redd [aut, cre] (<https://orcid.org/000-0002-6149-2438>),
R Documentation Task Force [ctb] (https://rdoctaskforce.github.io/),
R Consortium [fnd, cph] (https://www.r-consortium.org)