Title: Whole-Genome Sequencing Data Analysis via Knockoff Statistics
Description: Functions for identification of putative causal loci in whole-genome sequencing data. The functions allow genome-wide association scan. It also includes an efficient knockoff generator for genetic data.

Depends: R(>= 3.5.0), Matrix, seqminer, bigmemory
Imports: CompQuadForm, data.table, SPAtest, irlba

Title: Trio Data Analysis with Knockoff Statistics for FDR Control
Description: Identification of putative causal variants in genome-wide association studies with trio design.

Description: Identification of putative causal variants in genome-wide association studies with the trio design. The package implements the methods in the paper: Yang, Y., Wang, C., Liu, L., Buxbaum, J., He, Z., & Ionita-Laza, I. (2022). KnockoffTrio: A knockoff framework for the identification of putative causal variants in genome-wide association studies with trio design. The American Journal of Human Genetics, 109(10), 1761-1776.

Authors@R: c(person("Pavel Pimenov", role=c("aut", "cre"), email="pimenov@knoema.com"),
Description: Using this package, users can access to the largest collection of public data and statistics on the Internet featuring about 2.5 billion time series from thousands of sources collected in 'Knoema' repository and use rich R calculations in order to analyze the data. Because data in 'Knoema' is time series data, 'Knoema' function offers data in a number of formats usable in R such as 'ts', 'xts' or 'zoo'. For more information about 'Knoema' API go to <https://knoema.com/dev/docs>.
Imports: httr, jsonlite, base64enc, digest, lubridate, xts, zoo,

Packaged: 2021-11-02 08:24:12 UTC; afilippov

Packaged: 2021-11-02 15:47:46 UTC; afilippov

Description: 'Knoema' has the largest collection of public data and statistics on the Internet featuring about 2.5 billion time series from thousands of sources. Using 'Knoema' API users can access the data in the 'Knoema' repository and use rich R calculations in order to analyze the data. Because data in 'Knoema' is time series data, 'Knoema' function offers data in a number of formats usable in R such as 'ts', 'xts' or 'zoo'. For more information about 'Knoema' API go to <https://knoema.com/dev/docs>.