Description: Implements multinomial CDF (P(N1<=n1, ..., Nk<=nk)) and tail probabilities (P(N1>n1, ..., Nk>nk)), as well as probabilities with both constraints (P(l1<N1<=u1, ..., lk<Nk<=uk)). Uses a method suggested by Bruce Levin (1981) <doi:10.1214/aos/1176345593>.

person("Gavin", "Cooper", email = "gavin@gavincooper.net", role = c("aut", "cre", "trl"), comment = "Package creator and maintainer"),
person("Reilly", "Innes", email = "Reilly.Innes@uon.edu.au", role = c("aut")),
person("Caroline", "Kuhne", email = "caroline.kuhne@newcastle.edu.au", role = c("aut")),
person("Jon-Paul", "Cavallaro", email = "jon-paul.cavallaro@uon.edu.au", role = c("aut")),
person("David", "Gunawan", email = "dgunawan@uow.edu.au", role = c("aut"), comment = "Author of original MATLAB code"),
person("Guy", "Hawkins", email = "guy.hawkins@newcastle.edu.au", role = c("aut")),
person("Scott", "Brown", email = "scott.brown@newcastle.edu.au", role = c("aut", "trl"), comment = "Original translation from MATLAB to R"))
Description: Provides an R implementation of the Particle Metropolis within
Gibbs sampler for model parameter, covariance matrix and random effect
estimation. A more general implementation of the sampler based on the paper
by Gunawan, D., Hawkins, G. E., Tran, M. N., Kohn, R., & Brown, S. D.
(2020) <doi:10.1016/j.jmp.2020.102368>. An HTML tutorial document describing
the package is available at <https://newcastlecl.github.io/samplerDoc/> and
includes several detailed examples, some background and troubleshooting
Imports: coda, condMVNorm, MASS, MCMCpack, mvtnorm, stats
Author: Gavin Cooper [aut, cre, trl] (Package creator and maintainer),
David Gunawan [aut] (Author of original MATLAB code),
Scott Brown [aut, trl] (Original translation from MATLAB to R)

Imports: checkmate, coda, condMVNorm, MASS, MCMCpack, mvtnorm, stats

Title: Pharmacometric and Pharmacokinetic Toolkit
Authors@R: c(person("Justin", "Wilkins", email = "justin.wilkins@occams.com", role = c("aut", "cre")),
person("E. Niclas", "Jonsson", email="niclas.jonsson@pharmetheus.com", role="ctb"),
person("Mats O.", "Karlsson", email="mats.karlsson@farmbio.uu.se", role="ctb"),
Description: Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given
times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero-
and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008)
<http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates
and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).
Imports: grid, stats, utils, MASS, XML, stringr, ggplot2, xpose,