Title: Kernel Based Gradient Matching for Parameter Inference in
Authors@R: person("Mu", "Niu", email = "mu.niu@plymouth.ac.uk", role = c("aut","cre"))
Description: The kernel ridge regression and the gradient matching algorithm proposed in Niu et al. (2016) <http://jmlr.org/proceedings/papers/v48/niu16.html> and the warping algorithm proposed in Niu et al. (2017) <DOI:10.1007/s00180-017-0753-z> are implemented for parameter inference in differential equations. Four schemes are provided for improving parameter estimation in odes by using the odes regularisation and warping.

Authors@R: person("Mu", "Niu", email = "mu.niu@glasgow.ac.uk", role = c("aut","cre"))

Description: The kernel ridge regression and the gradient matching algorithm proposed in Niu et al. (2016) <https://proceedings.mlr.press/v48/niu16.html> and the warping algorithm proposed in Niu et al. (2017) <DOI:10.1007/s00180-017-0753-z> are implemented for parameter inference in differential equations. Four schemes are provided for improving parameter estimation in odes by using the odes regularisation and warping.

Title: Methods for Calculating 'KHQ' Scores and 'KHQ5D' Utility Index
Description: The King's Health Questionnaire (KHQ) is a disease-specific,
self-administered questionnaire designed specific to assess the impact of
Urinary Incontinence (UI) on Quality of Life. The questionnaire was developed
It is a simple, acceptable and reliable measure to use in the clinical setting
and a research tool that is useful in evaluating UI treatment outcomes.
The KHQ five dimensions (KHQ5D) is a condition-specific preference-based
measure developed by Brazier and collaborators (2008) <doi:10.1177/0272989X07301820>.
Although not as popular as the SF6D <doi:10.1016/S0895-4356(98)00103-6> and
EQ-5D <https://euroqol.org/>, the KHQ5D measures health-related quality of
life (HRQoL) specifically for UI, not general conditions like the others
two instruments mentioned. The KHQ5D ca be used in the clinical and economic
evaluation of health care. The subject self-rates their health in terms of
five dimensions: Role Limitation (RL), Physical Limitations (PL), Social
Limitations (SL), Emotions (E), and Sleep (S). Frequently the scores on these
five dimensions are converted to a single utility index using country specific
value sets, which can be used in the clinical and economic evaluation of
health care as well as in population health surveys. This package provides
methods to calculate scores for each dimension of the KHQ; converts KHQ item
scores to KHQ5D scores; and also calculates the utility index of the KHQ5D.
Maintainer: Luiz Augusto Brusaca <augustobrusaca@gmail.com>