Author: Derek Pappas <dpappas@chori.org>, Steve Mack <sjmack@chori.org>, Jill
Description: Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.
Imports: XML, haplo.stats, parallel, knitr, rmarkdown

Packaged: 2017-07-19 05:28:23 UTC; PappasDesktop

Packaged: 2017-07-10 05:52:04 UTC; PappasDesktop

Packaged: 2017-09-06 05:58:11 UTC; PappasDesktop

Description: Data sets and functions for chi-squared Hardy-Weinberg and case-
control association tests of highly polymorphic genetic data [e.g., human
leukocyte antigen (HLA) data]. Performs association tests at multiple levels of
polymorphism (haplotype, locus and HLA amino-acids). Combines rare variants to
a common class to account for sparse cells in tables as described by Hollenbach
JA, Mack SJ, Thomson G, Gourraud PA. 'Analytical methods for disease association
studies with immunogenetic data.' Methods Mol Biol. 2012;882:245-66.

Description: Data sets and functions for chi-squared Hardy-Weinberg and case-control
association tests of highly polymorphic genetic data [e.g., human leukocyte antigen
(HLA) data]. Performs association tests at multiple levels of polymorphism
(haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA,
Mack SJ. 2016. 'Bridging ImmunoGenomic Data Analysis Workflow Gaps (BIGDAWG):
An integrated case-control analysis pipeline.' Human Immunology, article in press.
Combines rare variants to a common class to account for sparse cells in tables as
described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA. 'Analytical methods
for disease association studies with immunogenetic data.' Methods Mol Biol. 2012;
Packaged: 2016-02-19 19:52:05 UTC; Pappas Family