Title: Exploring Disease Similarity in Terms of Dysfunctional
Description: Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug repositioning. This package was designed and implemented for identifying disease similarities. It contains five functions which are 'DCEA', 'DCpathway', 'DS', 'comDCGL' and 'comDCGLplot'. In 'DCEA' function, differentially co-expressed genes and differentially co-expressed links are extracted from disease vs. health samples. Then 'DCpathway' function assigns differential co-expression values of pathways to be the average differential co-expression value of their component genes. Then 'DS' employs partial correlation coefficient of pathways as the disease similarity for each disease pairs. And 'DS' contains a permutation process for evaluating the statistical significant of observed disease partial correlation coefficients. At last, 'comDCGL' and 'comDCGLplot' sort out shared differentially co-expressed genes and differentially co-expressed links with regulation information and visualize them.
Packaged: 2015-05-12 09:02:55 UTC; Administrator

Title: A Wrapper of the JavaScript Library 'DataTables'
person("Yihui", "Xie", email = "xie@yihui.name", role = c("aut", "cre")),
person("Joe", "Cheng", email = "joe@rstudio.com", role = c("ctb")),
person("jQuery contributors", role = c("ctb", "cph"), comment = "jQuery in htmlwidgets/lib"),
person("SpryMedia Limited", role = c("ctb", "cph"), comment = "DataTables in htmlwidgets/lib"),
person("Brian", "Reavis", role = c("ctb", "cph"), comment = "selectize.js in htmlwidgets/lib"),
person("Leon", "Gersen", role = c("ctb", "cph"), comment = "noUiSlider in htmlwidgets/lib"),
person("Bartek", "Szopka", role = c("ctb", "cph"), comment = "jquery.highlight.js in htmlwidgets/lib"),
Description: Data objects in R can be rendered as HTML tables using the
JavaScript library 'DataTables' (typically via R Markdown or Shiny). The
'DataTables' library has been included in this R package. The package name
'DT' is an abbreviation of 'DataTables'.
Imports: htmltools, htmlwidgets (>= 0.4), magrittr
jQuery contributors [ctb, cph] (jQuery in htmlwidgets/lib),
SpryMedia Limited [ctb, cph] (DataTables in htmlwidgets/lib),
Brian Reavis [ctb, cph] (selectize.js in htmlwidgets/lib),
Leon Gersen [ctb, cph] (noUiSlider in htmlwidgets/lib),
Bartek Szopka [ctb, cph] (jquery.highlight.js in htmlwidgets/lib),