Dependency analysis on package VariantAnnotation

General information

Bioconductor link link
Package version1.42.1
Number of strong dependencies98
Number of all dependencies152
Number of parent packages20
Max heaviness from parent packages26
Total heaviness from parent packages27
Number of parent packages (including Suggests and Enhances)31
Max co-heaviness from parent packages ("GenomicFeatures" and "AnnotationDbi")25

Dependency heatmap

In the following dependency heatmap, rows are the parent packages of VariantAnnotation and columns are the dependency packages that each parent package brings in. On the right side of the heatmap, there are three barplot annotations: 1. number of imported functions/S4 methods/S4 classes from parent packages; 2. number of dependency packages from each parent package; 3. heaviness of each parent package on VariantAnnotation.

Adjust heatmap size:
Base packages Other packages Depends Imports LinkingTo Suggests methods utils graphics stats stats4 tools grDevices grid parallel splines BiocGenerics S4Vectors zlibbioc IRanges RCurl GenomeInfoDbData bitops GenomeInfoDb XVector crayon GenomicRanges Biobase Matrix lattice Biostrings matrixStats yaml MatrixGenerics DelayedArray BiocParallel Rhtslib futile.logger snow codetools BH lambda.r futile.options formatR rlang R6 glue pkgconfig vctrs jsonlite cli fastmap XML Rsamtools GenomicAlignments BiocIO restfulr SummarizedExperiment rjson digest magrittr DBI RSQLite KEGGREST bit64 blob memoise Rcpp plogr httr png bit cachem curl mime openssl askpass sys rtracklayer rappdirs ellipsis lifecycle pillar tibble withr fansi utf8 AnnotationDbi stringr BiocFileCache stringi dbplyr dplyr filelock assertthat purrr tidyselect generics biomaRt progress xml2 hms prettyunits BSgenome GenomicFeatures VariantAnnotation BiocManager htmltools bslib jquerylib base64enc sass fs survival bookdown knitr rmarkdown xfun tinytex evaluate highr gtable isoband MASS mgcv scales nlme farver labeling munsell RColorBrewer viridisLite colorspace BiocVersion interactiveDisplayBase shiny DT httpuv xtable fontawesome sourcetools later promises commonmark htmlwidgets crosstalk lazyeval 0 5 10 Imported methods 0 50 100 Required packages 0 10 20 Heaviness from parents methods MatrixGenerics BiocGenerics GenomeInfoDb GenomicRanges SummarizedExperiment Rsamtools utils zlibbioc DBI Biobase S4Vectors IRanges XVector Biostrings AnnotationDbi rtracklayer BSgenome GenomicFeatures Rhtslib RUnit snpStats SNPlocs.Hsapiens.dbSNP.20101109 BiocStyle ggplot2 BSgenome.Hsapiens.UCSC.hg19 AnnotationHub TxDb.Hsapiens.UCSC.hg19.knownGene SIFT.Hsapiens.dbSNP132 SIFT.Hsapiens.dbSNP137 PolyPhen.Hsapiens.dbSNP131 In total 98 packages are required directly or indirectly (152) when installing 'VariantAnnotation' (1.42.1) Depends Imports LinkingTo Suggests Base packages that are required Recommended packages that are required Contributed packages that are required Packages that are required for installing 'VariantAnnotation' Imported functions Imported S4 methods Imported S4 classes The whole namespace is imported Package is listed in 'Imports' but namespace is not imported


Dependency table

"Import" information is from the NAMESPACE file of VariantAnnotation.

imports: number of imported functions/objects; importMethods: number of imported S4 methods; importClasses: number of imported S4 classes.

Required packages: number of strong dependency packages for each of the parent package (or in other words, number of dependency packages the parent package brings in).

Heaviness from parent on VariantAnnotation: number of required packages that can be reduced if moving parent package to Suggests of VariantAnnotation.

Parent package Field imports importMethods importClasses Required packages Heaviness from parent on VariantAnnotation
methods Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 0 0
MatrixGenerics Depends 1 0 0 2 0
BiocGenerics Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 4 0
GenomeInfoDb Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 11 0
GenomicRanges Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 15 0
SummarizedExperiment Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 24 0
Rsamtools Depends The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 29 0
GenomicFeatures Imports 4 7 1 96 26
BSgenome Imports 0 0 1 45 1
utils Imports 3 0 0 0 0
zlibbioc Imports The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 0 0
DBI Imports 0 9 0 1 0
Biobase Imports 3 0 1 5 0
S4Vectors Imports The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 6 0
IRanges Imports The whole set of functions/methods/classes from parent package is imported to the namespace of VariantAnnotation. 7 0
XVector Imports 2 0 0 10 0
Biostrings Imports 6 4 2 17 0
AnnotationDbi Imports 0 8 1 44 0
rtracklayer Imports 2 0 0 44 0
Rhtslib LinkingTo Parent package is listed in LinkingTo of VariantAnnotation but no object from parent package is imported. 1 0
AnnotationHub Suggests No object is imported into the namespace of VariantAnnotation. 85 22
BiocStyle Suggests No object is imported into the namespace of VariantAnnotation. 30 15
ggplot2 Suggests No object is imported into the namespace of VariantAnnotation. 37 14
snpStats Suggests No object is imported into the namespace of VariantAnnotation. 12 3
SIFT.Hsapiens.dbSNP132 Suggests No object is imported into the namespace of VariantAnnotation. 99 2
SIFT.Hsapiens.dbSNP137 Suggests No object is imported into the namespace of VariantAnnotation. 99 2
PolyPhen.Hsapiens.dbSNP131 Suggests No object is imported into the namespace of VariantAnnotation. 99 2
RUnit Suggests No object is imported into the namespace of VariantAnnotation. 3 1
SNPlocs.Hsapiens.dbSNP.20101109 Suggests No object is imported into the namespace of VariantAnnotation. 16 1
BSgenome.Hsapiens.UCSC.hg19 Suggests No object is imported into the namespace of VariantAnnotation. 46 1
TxDb.Hsapiens.UCSC.hg19.knownGene Suggests No object is imported into the namespace of VariantAnnotation. 97 1

The following table lists pairs of parent packages with co-heaviness larger than 10. The co-heaviness measures the number of additional dependencies that two parent packages simultaneously import and are only imported by the two parents.

Note the co-heaviness from parents can be always easily observed in the dependency heatmap.

Parent 1 Parent 2 Co-heaviness on VariantAnnotation Co-heaviness as Jaccard coeffcient
AnnotationDbi GenomicFeatures 25 0.49

Analysis was done with pkgndep.